Proteome Analysis
Guild BioSciences offers proteome analysis for your protein of interest. Many of these services are the same standard biological laboratory techniques used around the world. However, in our experience, seemingly minor tweaks in process or results interpretation often determine the success of a project. This is a core principle; therefore, our PhD experts are intimately involved in each service we perform. We do not guarantee our services will be the least expensive option available, but rather, that the quality and professionalism of our service is unrivaled. You will receive individual attention from an expert in protein purification and proteomic methods that will ensure the results you need.
SDS PAGE, Two-Dimensional Electrophoresis (2DE)
Standard gels are processed with the care of a professional. Differential analysis includes spot detection, characterization, and comparison as well as intra- and inter-experimental group analyses.
Rapid Analysis Meso-Resolution (RAMRTM) Protein Profiling
A Guild BioSciences innovation in protein profiling, this pioneering process incorporates a proprietary pre-fractionation method, which is used to amplify low-abundance protein signals. Contact us about the suitability for use with your target protein as it is an excellent choice for preliminary proteomic screening when time is at a premium.
Differential Proteomic Analysis
Once a 2DE separation has been performed, more protein details can be gathered from the gel. Our differential proteomic analysis service involves a series of computer-based applications that reveal important information about your protein material. Using Phoretix 2D Evolution software (Nonlinear Dynamics), we can generate a variety of reports related to spot detection, characterization, and comparison as well as intra- and inter-experimental group analyses
High-Resolution Proteomic Analysis using Pre-fractionation
Relative to standard 2DE outcomes, high-resolution proteomic analysis results in improved sensitivity and superior resolution of your protein fractions. Our enhanced results are due to the application of an optimized chromatographic pre-fractionation prior to 2DE analysis. Additionally, we can work with you to develop customized chromatographic pre-fractionations, if desired.
