Publications

Listed below are publications, convention presentations, and convention posters made by Guild BioSciences scientists. While not all topics are within the current scope of Guild Associates research, we do welcome all inquiries regarding collaboration or partnerships.

For presentations and posters, the medium can be viewed by clicking on the link.

For publications, the abstract can be viewed by clicking the “View Abstract” button.  �

Schofield, D. A., Molineux, I. J. and Westwater, C. 2011. Bioluminescent reporter phage for the detection of category A bacterial pathogens. http://www.jove.com/details.php?id=2740 doi: 10.3791/2740. Journal of Visualized Experiments, 53.

Smiechowski, M.F., Lvovich, V.F., Srikanthan, S. and Silverstein, R.L. 2011. Non-linear impedance characterization of blood cells-derived microparticle biomarkers suspensions. Electrochimica Acta, 56: 7763-7771.

Schofield, D. A., Molineux, I. and Westwater, C. 2011. Anthrax and plague diagnostic identification, and antibiotic susceptibility testing using bioluminescent reporter phage. 9th ASM Biodefense and Emerging Diseases Research Meeting, Washington, DC, February 6th-9th, 2011.

Schofield, D. A., Molineux, I. J., and Westwater, C. 2009. Diagnostic bioluminescent phage for the detection of Yersinia pestis. Journal of Clinical Microbiology, 47(12):3887-94.

Schofield, D. A. and DiNovo, A. 2010. Generation of a mutagenized organophosphorus hydrolase for the biodegradation of the organophosphate pesticides malathion and demeton-S. Journal of Applied Microbiology, 109(2):548-557.

Schofield, D. A. and Westwater, C. 2009. Phage-mediated bioluminescent detection of Bacillus anthracis. Journal of Applied Microbiology, 107(5):1468-78.

Schofield, D. A., Frank, M. B., Balish, E. and Westwater, C. 2008. In vivo transcriptional profiling of Candida albicans during the commensal to pathogenic transition. American Society of Microbiology meeting on Candida and Candidiasis, Jersey, NJ.

Schofield, D.A., Westwater, C., Barth, J. L. and DiNovo, A. A. 2007. Development of a yeast biosensor-biocatalyst for the detection and biodegradation of paraoxon. Applied Microbiology and Biotechnology, 76(6):1383-94.

Westwater, C., Balish E., Warner, T. F., Nicholas, P. J., Paulling, E. E. and Schofield, D.A. 2007. Susceptibility of gnotobiotic transgenic mice (Tge26) with combined deficiencies in natural killer cells and T cells to wild-type and hyphal signaling-defective mutants of Candida albicans. Journal of Medical Microbiology, 56(9):1138-1144.

Westwater, C., Schofield, D.A., Nicholas, P. J., Paulling, E. E. and Balish, E. 2007. Candida glabrata and Candida albicans; dissimilar tissue tropism and infectivity in a gnotobiotic model of mucosal candidiasis. FEMS Immunology and Medical Microbiology, 51(1):134-139.

DiNovo, A.A., Schey, K.L., Vachon, W.S., McGuffie, E.M., Olson, J.C. and Vincent, T.S. 2006. ADP-ribosylation of cyclophilin A by Pseudomonas aeruginosa exoenzyme S. Biochemistry, 45(14):4664-4673.

Balish, E., Warner, T., Nicholas, P., Paulling, E.E., Westwater, C. and Schofield, D.A. 2006. Susceptibility of gp91PHOX-/-/NOS2-/- knockout mice, defective in the production of reactive metabolites of oxygen (ROI) and nitrogen (RNI), to mucosal and systemic candidiasis of endogenous origin. Infection and Immunity, 73(3):1313-1320.

Schofield, D.A., Westwater, C. and Balish, E. 2005. Divergent chemokine, cytokine and ß-defensin responses to gastric candidiasis in immunocompetent C57BL/6 and BALB/c mice. Journal of Medical Microbiology, 54:87-92.

Schofield, D. A., Westwater, C., Warner, T. and Balish, E. 2005. Differential Candida albicans lipase gene expression during alimentary tract colonization and infection. FEMS Microbiology Letters, 244:359-365.

Westwater, C., Balish, E. and Schofield, D.A. 2005. Candida albicans-conditioned media protects cells from oxidative stress: a possible link between quorum-sensing and oxidative stress resistance. Eukaryotic Cell, 4(10):1654-1661.

Schofield, D.A., Westwater, C. and Balish, E. 2004. ß-defensin expression in immunocompetent and immunodeficient germfree and Candida albicans monoassociated mice. Journal of Infectious Diseases, 190:1327-1334.

Schofield, D.A., Westwater, C., Hoel, B.D., Werner, P.A., Norris, J.S. and Schmidt, M.G. 2003. Development of a thermally regulated broad-spectrum promoter system for use in pathogenic Gram-positive species. Applied and Environmental Microbiology, 69(6):3385-3392.

Schofield, D.A., Westwater, C., Paulling, E.E., Nicholas, P.J. and Balish, E. 2003. Detection of Candida albicans mRNA from formalin-fixed, paraffin-embedded mouse tissue by nested reverse transcription-PCR. Journal of Clinical Microbiology, 41:831-834.

Schofield, D.A., Westwater, C., Warner, T., Nicholas, P.J., Paulling, E.E. and Balish, E. 2003 Hydrolytic gene expression during oroesophageal and gastric candidiasis in immunocompetent and immunodeficient gnotobiotic mice. Journal of Infectious Diseases, 188:591-599.

Westwater, C., Kasman, L.M., Schofield, D.A., Werner, P.A., Dolan, J.W., Schmidt, M.G. and Norris, J.S. 2003. Use of a genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for the treatment of bacterial infections. Antimicrobial Agents and Chemotherapy, 47:1301-1307.

Schofield, D.A., Westwater, C., Dolan, J.W., Norris, J.S. and Schmidt, M.G. 2002. Doc-mediated cell killing in Shigella flexneri using a C1/LacI controlled expression system. FEMS Microbiology Letters, 215:237-242.

Schofield, D.A., Westwater, C., Dolan, J.W., Norris, J.S. and Schmidt, M.G. 2002. Tight regulation and modulation via a C1-regulated promoter in Escherichia coli and Pseudomonas aeruginosa. Current Microbiology, 44:425-430.

Westwater, C., Schofield, D.A., Schmidt, M.G., Norris, J.S. and Dolan, J.W. 2002. Development of a P1 phagemid system for the delivery of DNA into Gram-negative bacteria. Microbiology, 148:943-950.

Schofield, D.A., Westwater, C., Dolan, J.W., Schmidt, M.G. and Norris, J.S. 2001. Controlled expression in Klebsiella pneumoniae and Shigella flexneri using a bacteriophage P1-derived C1-regulated promoter system. Journal of Bacteriology, 183:6947-6950.

Ringwood, A.H., Conners, D.E. and DiNovo, A.A.. 1998. Effects of copper exposures on cellular responses in oysters. Marine Environmental Research, 46(1-5):591-95.

Nath, N., Khan, M., Rattan, R., Mangalam, A., Makkar, R.S., de Meester, C., Bertrand, L., Singh, I., Chen, Y., Viollet, B. and Giri, S. 2009. Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity. Biochemical and Biophysical Research Communications, 386(1):16-20.

Mathis, B.J., Marshall, C.W., Milliken, C.E., Makkar R.S., Creager S.E. and May H.D. 2007. Electricity generation by thermophilic microorganisms from marine sediment. Applied Microbiology and Biotechnology, 78(1):147-55.

Makkar, R.S., Contreras, M.A., Paintlia, A.S., Smith, B.T., Haq, E. and Singh, I. 2006. Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix. Archives of Biochemistry and Biophysics, 451(2):128-40.

Jayaraj, J., Rockne, K.J. and Makkar R.S. 2004. Reductive dechlorination of tetrachloroethene by a mixed bacterial culture growing on ethyl lactate. Journal of Environmental Science and Health Part A – Toxic/Hazardous Substances & Environmental Engineering, 39(6):1399-414.

Cameotra, S.S. and Makkar R.S. 2004. Recent applications of biosurfactants as biological and immunological agents. A review. Current Opinion in Microbiology, 7(3):262-266.

Makkar, R.S. and Cameotra, S.S. 2002. An update on the unconventional substrates for the biosurfactant production and their (new) applications. Applied Microbiology and Biotechnology, 58:428-434.

Makkar, R.S. and Cameotra, S.S. 2002. Effects of various nutritional supplements on biosurfactant production by a strain of Bacillus subtilis at 45°C. Journal of Surfactants and Detergents, 5:1117.

Makkar, R.S. and Cameotra, S.S. 2001. Synthesis of enhanced biosurfactant by Bacillus subtilis MTCC 2423 at 45* C by foam fractionation. Journal of Surfactants and Detergents, 4(3):355-357.

Makkar R.S., Tsuneda A., Tokuyasu, K., and Mori, Y. 2001. Lentinula edodes produces a multicomponent protein complex containing manganese (II)-dependent peroxidase, laccase and -glucosidase. FEMS Microbiology Letters, 200:175-179.

Rockne, K.J. and Makkar, R.S. 2001. Anaerobic Electron Acceptor Amendment for aromatic pollutant biodegradation in sediments. In Situ and On- site Bioremediation, 6(5):297-304.

Banat, I.M., Makkar, R.S. and Cameotra, S.S. 2000. Potential commercial applications of microbial surfactants. Applied Microbiology and Biotechnology, 53:495-508.

Makkar, R.S. and Cameotra, S.S. 1999. Biosurfactant production by microorganisms on unconventional carbon sources. Journal of Surfactants and Detergents, 2:237-241.

Makkar, R.S. and Cameotra, S.S. 1999. Structural characterization of a biosurfactant produced by Bacillus subtilis at 45°C. Journal of Surfactants and Detergents, 2:367-372.

Makkar, R.S. and Cameotra, S.S. 1998. Production of biosurfactant at mesophilic and thermophilic conditions by a strain of Bacillus subtilis. Journal of Industrial Microbiology and Biotechnology, 20:48-52.

Cameotra, S.S. and Makkar, R.S. 1998. Synthesis of biosurfactant under extreme conditions – A review. Applied Microbiology and Biotechnology, 50:520-529.

Makkar, R.S. and Cameotra, S.S. 1997. Biosurfactant production by a thermophilic Bacillus subtilis strain. Journal of Industrial Microbiology and Biotechnology, 18:37-42.

Makkar, R.S. and Cameotra, S.S. 1997. Utilization of molasses for biosurfactant production by two Bacillus strains at thermophilic conditions. Journal of the American Oil Chemists’ Society (JACOS), 74(7):887-889.