Augustine (Gus) DiNovo Ph.D:
Dr. DiNovo has been involved in protein purification and analysis for over ten years having experience in both chromatographic and electrophoretic protein analysis. During his dissertation work at the Medical University of South Carolina, Dr. DiNovo developed a strong expertise in size exclusion chromatography, ion exchange chromatography, reversed phase HPLC, and two-dimensional electrophoresis (2DE). He also became experienced in preparative electrophoresis, capillary electrophoresis, SDS PAGE, and LC-MS and MALDI TOF MS. He further refined his expertise in 2DE during his post-doctoral work, and subsequent employment at Guild Associates, Inc. While at Guild, Dr. DiNovo conducted extensive optimization research in 2DE procedures, which resulted in the development of a novel pre-fractionation procedure that significantly increases the resolution and sensitivity of standard 2DE analysis. Guild is currently in the process of developing the procedure for commercial production. Dr. DiNovo is also knowledgeable in marine biology, having received an MS in the field. He has participated in extensive field-based fisheries research, and also has experience in managing marine husbandry facilities.

Dr. Gus DiNovo is experienced in the following technical areas:

Protein: Two-Dimensional Electrophoresis SDS PAGE Capillary Electrophoresis Preparative Electrophoresis Unit (Biorad) Size-Exclusion Chromatography Ion Exchange Chromatography Hydrophobic Interaction▪Chromatography Reversed-Phase High Performance Liquid Chromatography (RP-HPLC) Affinity Chromatography Atomic Absorption Spectrometry UV/VIS Spectrophotometry Mass Spectrometry : Electrospray Triple Quadrapole (Sciex) Ion Trap (Finnigan) MS MALDI TOF MS Total Sulfhydryl Analysis Protein Precipitation Fractionation Temperature-Based Protein Fractionation Ultrafilteration/Concentration

Nucleic acids: Total RNA Isolation RT-PCR DNA Sequencing Whole Organism Analysis: Invertebrate and Vertebrate Dissection Invertebrate Primary Culture Development Morphometric Analysis Fish Assemblage and Identification Fish Bone and Muscle Morphological Analysis Fisheries Sample Collection

See the Guild BioScience Team Projects and Publications.

David A. Schofield, Ph.D:
Dr. Schofield has extensive expertise in molecular microbiology. Dr. Schofield graduated with a Bachelor of Science Honors degree in Microbiology at the University of Aberdeen, Scotland where he also obtained his Ph.D in Molecular Mycology. His postdoctoral work at the Medical University of South Carolina, consisted of studying the expression of a glutathione S-transferase gene during hormonal carcinogenesis, developing a novel bacteriophage-based strategy for the treatment of antibiotic-resistant bacteria, and elucidating the virulence factors that are required for infection by the human pathogenic fungus Candida albicans. He has published 17 research papers in scientific journals and 2 book chapters. Dr. Schofield joined Guild Associates, Inc., in October 2004.

Dr. Schofield is experienced in the following technical areas:

See the Guild BioScience Team Projects and Publications.

Extended Technical Support:
Guild BioSciences provides proteomic and molecular biology services and research from the Charleston, South Carolina laboratory center. The scientific team in Charleston is also supported by the Guild research and engineering staff in Columbus, Ohio. The Columbus headquarters has a technical staff of over 50 people including Ph.Ds, engineers and technicians in disciplines of chemistry, electronics, mechanics, biomedical engineering, electro-chemical sensors, programming and manufacturing.