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Guild Associates
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Publications
  • Schofield, D.A., Westwater, C., Barth, J. L. & DiNovo, A. A. 2007. Development of a yeast biosensor-biocatalyst for the detection and biodegradation of paraoxon. Applied Microbiology and Biotechnology 76(6):1383-94. View PubMed abstract

  • Westwater, C., Balish E., Warner, T. F., Nicholas, P. J., Paulling, E. E. and Schofield, D.A. 2007. Susceptibility of gnotobiotic transgenic mice (Tge26) with combined deficiencies in natural killer cells and T cells to wild-type and hyphal signaling-defective mutants of Candida albicans. Journal of Medical Microbiology 56(9):1138-1144. View PubMed abstract

  • Westwater, C., Schofield, D.A., P. J., Paulling, E. E. and Balish, E. 2007. Candida glabrata and Candida albicans; dissimilar tissue tropism and infectivity in a gnotobiotic model of mucosal candidiasis. FEMS Immunology and Medical Microbiology 51(1):134-139. View PubMed abstract

  • DiNovo, A.A., Schey, K.L., Vachon, W.S., McGuffie, E.M., Olson, J.C. and Vincent, T.S. 2006. ADP-ribosylation of cyclophilin A by Pseudomonas aeruginosa exoenzyme S, Biochemistry 45(14):4664-4673. View PubMed abstract

  • Balish, E., Warner, T., Nicholas, P., Paulling, E.E., Westwater, C. and Schofield, D.A. T.S. 2006 Susceptibility of gp91PHOX-/-/NOS2-/- knockout mice, defective in the production of reactive metabolites of oxygen (ROI) and nitrogen (RNI), to mucosal and systemic candidiasis of endogenous origin. Infection and Immunity 73(3):1313-1320. View PubMed abstract

  • Schofield, D.A., Westwater, C. and Balish, E. 2005. Divergent chemokine, cytokine and ß-defensin responses to gastric candidiasis in immunocompetent C57BL/6 and BALB/c mice. Journal of Medical Microbiology 54:87-92. View PubMed abstract

  • Schofield, D. A., Westwater, C. Warner, T. and Balish, E. 2005. Differential Candida albicans lipase gene expression during alimentary tract colonization and infection. FEMS Microbiology Letters 244:359-365. View PubMed abstract

  • Westwater, C., Balish, E. and Schofield, D.A. 2005. Candida albicans-conditioned media protects cells from oxidative stress: a possible link between quorum-sensing and oxidative stress resistance. Eukaryotic Cell 4(10):1654-1661. View PubMed abstract

  • Schofield, D.A., Westwater, C. and Balish, E. 2004. ß-defensin expression in immunocompetent and immunodeficient germfree and Candida albicans monoassociated mice. Journal of Infectious Diseases 190:1327-1334. View PubMed abstract

  • Schofield, D.A., Westwater, C., Hoel, B.D., Werner, P.A., Norris, J.S. and Schmidt, M.G. 2003. Development of a thermally regulated broad-spectrum promoter system for use in pathogenic Gram-positive species. Applied and Environmental Microbiology 69(6):3385-3392. [ View PubMed abstract

  • Schofield, D.A., , C., Paulling, E.E., Nicholas, P.J. and Balish, E. 2003. Detection of Candida albicans mRNA from formalin-fixed, paraffin-embedded mouse tissue by nested reverse transcription-PCR. Journal of Clinical Microbiology 41:831-834. View PubMed abstract

  • Schofield, D.A., Westwater, C., Warner, T., Nicholas, P.J., Paulling, E.E. and Balish, E. 2003 Hydrolytic gene expression during oroesophageal and gastric candidiasis in immunocompetent and immunodeficient gnotobiotic mice. Journal of Infectious Diseases 188:591-599. View PubMed abstract

  • Westwater, C., Kasman, L.M., Schofield, D.A., Werner, P.A., Dolan, J.W., Schmidt, M.G. and Norris, J.S. 2003. Use of a genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for the treatment of bacterial infections. Antimicrobial Agents and Chemotherapy 47:1301-1307. View PubMed abstract

  • Schofield, D.A., Westwater, C., Dolan, J.W., Norris, J.S. and Schmidt, M.G. 2002. Doc-mediated cell killing in Shigella flexneri using a C1/LacI controlled expression system. FEMS Microbiology Letters 215:237-242. View PubMed abstract

  • Schofield, D.A., Westwater, C., Dolan, J.W., Norris, J.S. and Schmidt, M.G. 2002. Tight regulation and modulation via a C1-regulated promoter in Escherichia coli and Pseudomonas aeruginosa. Current Microbiology 44:425-430. View PubMed abstract

  • Westwater, C., Schofield, D.A., Schmidt, M.G., Norris, J.S. and Dolan, J.W. 2002. Development of a P1 phagemid system for the delivery of DNA into Gram-negative bacteria. Microbiology 148:943-950. View PubMed abstract

  • Schofield, D.A., Westwater, C., Dolan, J.W., Schmidt, M.G. and Norris, J.S. 2001. Controlled expression in Klebsiella pneumoniae and Shigella flexneri using a bacteriophage P1-derived C1-regulated promoter system. Journal of Bacteriology 183:6947-6950. View PubMed abstract

  • Ringwood, A.H., Conners, D.E. and DiNovo, A.A.. 1998. Effects of copper exposures on cellular responses in oysters. Marine Environmental Research 46(1-5):591-95. View CSA Illumina abstract

Images A-E: Mouse tissue sections harvested from Candida albicans-infected tongues and sequence events of laser capture microdissection
To view examples of some of the exploratory experiments conducted at GBS related to protein methods, visit our Experiments page.
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